Modest Weight Gain Increases Breast Cancer Risk in Premenopausal Women

by Graham A. Colditz, MD, DrPH In a recent detailed analysis of weight change across the life course (funded by our NCI TREC center addressing obesity and cancer), we reported that short-term weight gain, defined as change over a 4-year time frame, significantly increased risk of both premenopausal and postmenopausal breast cancer (see report for […]

When are risk factors good for identifying women at high risk of cancer

Media coverage this week draws attention to a well-known fact in epidemiologic research. A risk factor alone does not always identify the top stratum of risk for a disease. Kerlikowske and colleagues from the NCI-funded breast cancer surveillance consortium draw on prospective data to demonstrate for women that a mammographic report of dense breasts is […]

CNiC’s Colditz Honored for Contributions to Prevention – Highlights Importance of Early Life in Breast Cancer Risk

Cancer News in Context’s Graham Colditz is being honored tonight at the American Association for Cancer Research Annual Meeting in Philadelphia, Pennsylvania as an AACR 2014-2015 Scientific Awardee. In the announcement of his 2014 Award for Outstanding Achievement in Cancer Prevention, AACR describes the honor and Colditz’s contributions to the field: The award is given […]

New Dietary Recommendations Take Innovative Approach – and Not Everyone’s Happy About It

By Yikyung Park, ScD Editor’s note: Not surprisingly, the recently released report from the Dietary Guidelines for Americans Advisory Committee was met with both praise and scorn.  Many in the medical and health fields lauded the report for its innovative approach to considering both the food environment and sustainability, as well as for its healthy […]

John Oliver Skewers Big Tobacco’s Heavy-Handed Global Efforts (Video)

We’re not prone to posting video clips from satirical news programs, but this weekend’s piece from Last Week Tonight with John Oliver really captured why it is so important to keep up the fight against Big Tobacco.  While we still have a great deal of work to do to get tobacco under control in the […]

Current Evidence on Smoking and Breast Cancer

Photo: flickr/saneboy (Creative Commons lic; cropped) Though the most recent Surgeon General’s report on the health effects of tobacco stops just short of classifying smoking as a cause of breast cancer, current evidence seems compelling enough to finally push tobacco smoke from simple risk factor to full-fledged “cause.” While research into the tobacco/breast cancer link […]

Study Finds Periods Start Earlier in Girls Who Drink a Lot of Sugary Drinks. What Does This Mean for Breast Cancer Risk?

Creative Commons photo (cropped): Flickr/zingersbs by Hank Dart A new study released last week in the journal Human Reproduction has found that regularly drinking sugar-sweetened beverages – like sodas and fruit drinks – may cause girls to start their menstrual periods at earlier ages.   The study, a spin off of the long-running Nurses’ Health […]

Screening for Cervical Cancer: Is the HPV Test a Good Alternative to the Pap Test?

By Sarah Cortez New guidelines from two professional medical organizations strongly suggest that the HPV (human Pap test micrograph. Photo: Flickr/euthman papilloma virus) test can be used on its own as an effective alternative to standard Pap tests in most women being screened for cervical cancer. For seventy years, the Pap test has been the […]

Preventing Skin Cancer: Tanning Beds Still Alluring, Still Very Risky

Photo: Flickr/whatshername, Creative Commons Lic. There was a nice piece in the New York Times this weekend on the risks of indoor tanning, particularly in youth. Focussing on the personal experiences of a handful of young women and their  parents, it does a very good job highlighting the well-established risks of skin cancer and deadly melanoma, the […]

Setting the Record Straight on Cancer Prevention: Lifestyle Trumps “Bad Luck”

While the paper by Tomasetti and Vogelstein is certainly intriguing and will help guide future research on targeting prevention and early detection efforts, it is still a preliminary finding and does not reverse the long-term conclusion that is supported by decades of well-designed research in people:  that cancer is largely preventable. –     –   […]

Healthy “Hoppin’ John” to Welcome 2015 (Recipe)

Creative Commons photo: Flickr/Robert S. Donovan (cropped) The holidays are filled with great-tasting but less-than-healthy food.  And that’s OK.  We all deserve some time to celebrate with our family and friends and enjoy food without worrying about its sodium, fat, and whole grain content.  As long as we don’t go too crazy and get back […]

2014’s Top Posts on Cancer News in Context

Amidst the crush of year-end top ten lists filling your news feeds this week, we present our own: the top posts of 2014 from Cancer News in Context. Covering topics from aspirin to healthy eating to the importance of starting healthy behaviors in childhood, these posts show the prominent place that cancer prevention has had […]

The Power of Youth: Beginning Breast Cancer Prevention in Childhood

Creative Commons photo: Flickr/CatDancing (cropped) We’ve written a lot recently about the importance of breast cancer prevention starting early in life, both here on Cancer News in Context and in a guest post on the American Association for Cancer Research blog, Cancer Research Catalyst.  Though most breast cancer research focusses on women in midlife and […]

HPV Vaccination Programs Shown Effective in Australia

Photo: Flickr/PAHOWHO by Sarah Cortez When given before the start of sexual activity, the HPV (human papillomavirus) vaccine prevents most cases of cervical cancer and genital warts. It can also lower the risk of oropharyngeal, penile and anal cancer. HPV is a sexually transmitted infection, and we target the vaccine to 11-12 olds, as we […]

PALB2 Mutation: A “New” Gene That Greatly Increases Breast Cancer Risk

Photo: Flickr/Micahb37 by Sarah CortezThere’s been a recent surge in women asking for genetic testing for breast cancer, due in large part to Angelina Jolie’s public decision last year to get a prophylactic mastectomy after discovering she had a mutation in the BRCA1 gene. These days, another breast cancer gene has been making headlines, a gene […]

Hormonal IUDs and Breast Cancer: Is There a Link?

by Sarah Cortez It certainly goes without saying that birth control has been a major news story the past couple of months. Much of this coverage, of course, has revolved around the recent Supreme Court ruling and reactions to it. Outside of that media storm, there have been some other health-related birth control stories as […]

Evolution of the Science on Aspirin Use and Colon Cancer Prevention

Yesterday, we posted about a new analysis suggesting that long term aspirin use is likely to have an overall health benefit in the general population even when its side effects are taken into account.  At risk of being wonky, we wanted to follow up on that with a figure that shows the general evolution of […]

An Aspirin a Day…May Have Overall Health Benefits

Photo: Flickr/JenR The writing was on the wall a few years ago, but it seems that we may have finally reached a point where the scientific evidence points pretty convincingly to the potential health benefits of long-term regular aspirin use outweighing the potential risks for most people. That’s the conclusion of a new analysis appearing last […]

Missed Opportunities to Prevent Cervical Cancer: Use of HPV Vaccine Still Low

Photo: Flickr/Melissa Wiese  To work in the field of cancer prevention one has to be an optimist at heart.  In the science, in the statistics, and in the news, you see not only the broad burden of cancer but also the vast opportunities that exist to lower risk and prevent the disease. At the same […]

Alcohol and Health: Three New Studies and What They Mean for Youth and Young Adults

Photo: Flickr/Tim RT It’s been a big week in the news for alcohol and health. Three separate studies were released that helped shed light on a key issue we often discuss here at Cancer News in Context: the important impact that drinking has on cancer risk – particularly when started early in life. The first […]

Time on the Side: New Analysis Finds That to Eat Less – Eat Slower

Photo: Flickr/thomashawk It probably comes as no surprise, but mom was right: We really shouldn’t eat so fast. Apart from the noise and the mess and the ill-effects on dinner table conversation, wolfing down food may have ill-effects on health as well. A detailed new analysis in the American Journal of Clinical Nutrition shows that […]

New Study: Tanning Bed Use Brings Skin Cancer Risks – and Brings Them Early

Photo: Flickr/whatshername A new study out this week further confirms the dangers of indoor tanning, finding that use of tanning beds and other UV tanning devices is strongly linked to developing skin cancer early in life. Published early online in the medical journal Pediatrics, the study compared the history of indoor tanning in a group […]

Data Show More Support Warranted for Worksite Wellness Programs

Photo: Flickr/abraj This week I had the privilege of addressing the American Cancer Society CEOs Against Cancer at their annual meeting that this year was held at Washington University in St. Louis. As a member of the panel addressing worksite wellness, I was able to briefly summarize the strong evidence that worksite wellness programs can […]

Sitting, Cancer Risk, and Developing Strategies to do Something About It

Photo: Flickr/DanielGo This post seems a bit cruel, coming out as it does during the current TV season’s finale week and the beginning of the World Cup.  But, science doesn’t rest – not even for Game of Thrones or the Brazilian national soccer team. So, neither do we. Just released on the Journal of the […]

ASCO Awards Lecture: Seizing the Opportunity for Cancer Prevention

Cancer News in Context‘s own Graham Colditz received the American Society of Clinical Oncology (ASCO)–American Cancer Society Award today at the ASCO Annual Meeting in Chicago (more info).  The award honors contributions to cancer prevention and control. In his associated lecture, Colditz will focus on the need to place a higher priority on prevention if […]

Innovation path to sustainable world – breast cancer prevention

I had the privilege of presenting in this thematic area for the Shanghai Forum and addressed the priority for prevention. This contrasted with a preceding talk that advocated for greater emphasis on genomic testing to focus prevention activities within the Chinese population. Using diabetes and breast cancer examples I contrasted the time course of disease […]

Letter to the Editor on Diet and Cancer: “No Myth”

Photo: Flickr/ToastyTreat As we mentioned in a previous post on CNiC, an article in the New York Times last week called the link between diet and cancer risk, in essence, a “myth.”  In that post, we note that “the article’s conclusions [about the links between diet and cancer] demonstrate a lack of understanding of the science.”  To further make […]

Setting the Record Straight: The Impact of Diet on Cancer Risk

Photo: Flickr/Mike65444 An article posted earlier this week on the New York Times website stated that the link between diet and cancer risk was, in essence, a “myth.”  And while links between diet and cancer are not as strong as those with some other chronic diseases, like heart disease, the article’s conclusions demonstrate a lack […]

Health behavior interventions prevent incidence and death from cancer

Flickr/NatalieMaynor At the annual meeting of the American Society for Preventive Oncology, I had the privilege of presenting the evidence that supports the potential for health behaviors and vaccines to have a huge payoff for prevention of cancer throughout the world. My slides from that talk are now available. Questions that I addressed include the […]

Take a Tour of the Zuum Risk Assessment App

  With some exciting projects coming down the pike for our Zuum risk assessment app for iPad, it seemed a great time to re-introduce Zuum with a video demonstration of all that it does.  Its engaging interface and strong evidence base make it a unique addition to the field of mHealth offerings.  With just a […]

(Video) Nuts Cut Risk of Cancer, Heart Disease, and Early Mortality

Earlier this month, we posted about recent findings linking nut consumption with a lower risk of benign breast disease in young women.  Further confirming the power of nuts, new results from a large study published in the New England Journal of Medicine reports that men and women who are frequent nut eaters (7 or more […]

Obesity shortening life among breast cancer survivors, national US data

Obesity is a strong driver for postmenopausal breast cancer. Consistent data from around the world show that overweight and obese women are at increased risk of breast cancer through their postmenopausal years. It is estimated that obesity causes more than 10% of postmenopausal breast cancer. Mechanisms for this include higher circulating estrogen levels among overweight […]

Prevention’s True Potential in the Ongoing “War on Cancer”

The latest in the New York Times‘ Retro Report series tackles the launch and subsequent progress of the Nixon administration’s 1971 National Cancer Act, dubbed the “War on Cancer.”  The ultimate hope of the act was that – with an economic and human power push similar to that used with the first moon landing in […]

Rosner-Colditz model predicting breast cancer risk outperforms Gail in independent cohort.

Validation of breast cancer risk prediction models in an independent prospective data set is rare. We drew on prospective data from the Nurses’ Health Study and the California Teachers Study to validate the Rosner-Colditz breast cancer incidence model and compare it to the Gail model.1 (see report) The Rosner-Colditz model includes a range of established […]

Reproductive risk factors drive risk of breast cancer in premenopausal women

To assess variation in the role of reproductive risk factors in relation to risk for breast cancer among premenopausal women we examined the relationship comparing women less than age 40 with older premenopausal women. Drawing on Data from the Nurses’ Health Studies, Dr. Warner and colleagues documented 374 incident cases of breast cancer diagnosed before […]

Breast cancer prevention should begin early in life

Breast cancer remains the second leading cause of cancer death among women. In the US it is estimated that 40,000 women will die from breast cancer in 2013. Just over 232,000 women will be diagnosed with breast cancer. Importantly, nearly a quarter of these new cases are diagnosed among women who are less than 50 […]

Mental health conditions negatively affect opportunity

“Mental health affects people’s social and economic opportunities, and in turn, social and economic opportunity affects mental health,” says Darrell L. Hudson, PhD, assistant professor in the Brown School at Washington University about a study aimed at improving mental health in St. Louis. Washington University public health science researchers Bettina F. Drake, PhD, and Melody […]

Preventing breast cancer: a diet with lots of fruits and vegetables

Let’s follow up on our recent post showing adolescent diet high in vegetable protein or nuts was associated with reduced risk of premalignant breast lesions in young adult women. (see previous post: Peanuts and lower risk of breast cancer)  This generated much interest and the potential of peanut butter to be of such major health benefit […]

Peanuts and lower risk of breast cancer

Media coverage today picked up on our paper published last week in breast cancer research and treatment (link). In that paper, we reported on the follow-up of women in the Growing Up Today’s Study. Over 9000 women were recruited to the study in 1996 when they were 9 to 15 years of age. The unique […]

In the News: Office Visits Can Reduce Youth Smoking & More Benefits Found for Mediterranean Diet

Hot off the presses this morning are two important health-related releases from the US Preventive Services Task Force and the Cochrane Library. From the USPSTF are updated recommendations that highlight effective approaches that primary care providers can use to prevent tobacco use in youth.  Because 90 percent of regular adult smokers begin smoking when they […]