Prostate Cancer Prospective Cohort

Faculty involved: Bettina Drake, Graham Colditz

The long-term goal of this collaboration between Dr. Drake and The St. Louis Mens Group Against Cancer is to be able to identify patients with increased risk for dying of prostate cancer while they are still treatable. The objective of this project is to maintain a biorepository (collection of prostate tissue, DNA and serum) and environmental data (i.e. diet, smoking, and exercise data) from patients with newly diagnosed, untreated prostate carcinoma. This proposal is based on the hypothesis that biological and environmental data can be used to predict risk of failure to respond to treatment. This study collects serum, tumor tissue, DNA, and questionnaire data as a resource for future studies assessing biologic correlates of metastatic disease.

Select Publications:

Imm KR, Williams F, Housten AJ, Colditz GA, Drake BF, Gilbert KL, & Yang L. African American prostate cancer survivorship: Exploring the role of social support in quality of life after radical prostatectomy. Journal of Psycholosocial Oncology. 2017 Apr 11; 35(4): 409-423.

Williams F, Imm KR, Colditz GA, Housten AJ, Yang L, Gilbert KL, & Drake BF. Physician role in physical activity for African-American males undergoing radical
prostatectomy for prostate cancer. Support Care Cancer. 2017 Apr;25(4):1151-1158. doi: 10.1007/s00520-016-3505-7. Epub 2016 Dec 21.

Wilson KM, Mucci LA, Drake BF, Preston MA, Stampfer MJ, Giovannucci E, & Kibel AS. Meat, Fish, Poultry, and Egg Intake at Diagnosis and Risk of Prostate Cancer Progression. Cancer Prev Res (Phila). 2016 Dec;9(12):933-941. Epub 2016 Sep 20.