For more details on our editorial this week in JAMA see the story from the Washington University School of Medicine news office.
We caution physicians and women to consider the broader body of evidence that even use of estrogen alone increases risk of breast cancer. This has been reiterated in several media stories covering the changing tide of evidence on hormones as a cause of breast cancer and factors such as obesity and time since menopause that are well documented to modify the effect of hormone therapy.
To place data on hormone therapy in context our Knol on breast cancer prevention provides a detailed summary.
Caution for estrogen therapy after hysterectomy