Su-Hsin Chang, PhD

Su-Hsin Chang

Assistant Professor
Division of Public Health Sciences
Department of Surgery
(314) 362-8623 

Research Overview
Dr. Chang is an applied econometrician and a health economist. Dr. Chang’s research focuses on health and economic consequences of obesity and surgical treatments of obesity. Her research uses economic and econometric/statistical modeling to evaluate program and treatment effects. Dr. Chang’s research areas include treatment effect and policy evaluation, cost-effectiveness analysis, meta-analysis, and comparative effectiveness.

Dr. Chang teaches “Decision Analysis for Clinical Investigation and Economic Evaluation" in the Master of Population Health Sciences program.

Research Staff

Nikki Freeman, Graduate Student Research Assistant

Zhongyu Li, Graduate Student Research Assistant

Carolyn Stoll, Program Coordinator

Select Publications
Yaghjyan L, Carlsson NP, Ghita GL, Chang S-H. Maternal exposure to di-2-ethylhexylphthalate and adverse delivery outcomes: a systematic review. Reprod Toxicol, 2016 Jul 10. pii: S0890-6238(16)30259-3. doi: 10.1016/j.reprotox.2016.07.002.

Yaghjyan L, Carlsson NP, Ghita GL, Chang S-H. Associations of individual characteristics and lifestyle factors with metabolism of di-2-ethylhexyl phthalate in NHANES 2001-2012. Environmental Research, 2016; Aug;149:23-31. doi: 10.1016/j.envres.2016.05.002. Epub 2016 May 9.

Samson P, Patel A, Robinson CG, Morgensztern D, Chang S-H, Colditz GA, Waqar S, Crabtree TD, Krupnick AS, Kreisel D, Patterson GA, Meyers BF, Puri V. The role of surgical resection in stage IIIA non-small cell lung cancer: a decision and cost-effectiveness analysis. Ann Thorac Surg. 2015 Dec;100(6):2026-32; discussion 2032. doi: 10.1016/j.athoracsur.2015.05.091. Epub 2015 Aug 25.

Yaghjyan L, Sites S, Ruan Y, Chang S-H. Associations of Urinary Phthalates with Body Mass Index, Waist Circumference, and Serum Lipids Among Females: National Health and Nutrition Examination Survey 1999-2004. International Journal of Obesity, 2015; 39: 994-1000.

Drake BF, Abadin SS, Lyons S, Chang S-H, Steward LT, Kraenzle S, Goodman MS. Mammograms on-the-go: predictors of repeat visits to mobile mammography vans in St. Louis, Missouri, USA – A case-control study. BMJ Open, 2015 Mar 20; 5(3): e006960.

Chang S-H, Luo S, O’Brian KK, Thomas TS, Colditz GA, Carlsson NP, Carson KR. Association between metformin use and progression of monoclonal gammopathy of undetermined significance to multiple myeloma in US veterans with diabetes mellitus: a population-based retrospective cohort study. The Lancet Haematology, 2015;2:30-36.

Leung M, Pollack LM, Colditz GA, Chang S-H. Life years lost and lifetime healthcare expenditures associated with diabetes in the U.S., National Health Interview Survey, 1997–2000. Diabetes Care, 2015;38:1-9.

Colditz GA, Bohlke K, Chang S-H, Carson KR. Energy Balance and Multiple Myeloma in African Americans. In: Bowen DJ, Denis GV, Berger NA, eds. Impact of Energy Balance on Cancer Disparities: Springer; 2014:119-129.

Yaghjyan L, Wolin K, Chang S-H, Colditz GA. Racial disparities in healthy behaviors and cancer screening among breast cancer survivors and women without cancer: National Health Interview Survey 2005. Cancer Causes Control. 2014 May;25(5):605-14. doi: 10.1007/s10552-014-0365-7. Epub 2014 Mar 18.

Chang S-H, Stoll CR, Song J, Varela JE, Eagon CJ, Colditz GA. The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003-2012. JAMA surgery. 2014 Mar;149(3):275-87. doi: 10.1001/jamasurg.2013.3654. Click here for supplemental material, including review protocol and additional articles.

Colditz GA, Chang S-H. The expanding potential for cohort studies to inform priorities for cancer prevention. Epidemiology. 2013 3:e112. doi: 10.4172/2161-1165.1000e112.

Chang S-H, Pollack LM, Colditz GA. Obesity, mortality, and life years lost associated with breast cancer in nonsmoking U.S. women, National Health Interview Survey, 1997–2000. Preventing Chronic Disease. 2013 Nov 14;10:E186. doi: 10.5888/pcd10.130112.

Beason TS, Chang S-H, Sanfilippo KM, Luo S, Colditz GA, Vij R, Tomasson MH, Dipersio JF, Stockerl-Goldstein K, Ganti A, Wildes T, Carson KR. Influence of body mass index on survival in veterans with multiple myeloma. Oncologist. 2013;18(10):1074-9. doi: 10.1634/theoncologist.2013-0015. Epub 2013 Sep 18.

Chang S-H, Pollack LM, Colditz GA. Life years lost associated with obesity-related diseases for U.S. nonsmoking adults. PLoS ONE 8(6): e66550. doi:10.1371/journal.pone.0066550.

Strope S, Chang S-H, Chen L, Sandhu G, Piccirillo JF, Schootman M. Survival Impact of followup care after radical cystectomy for bladder cancer. Journal of Urology. 2013 Nov;190(5):1698-703. doi: 10.1016/j.juro.2013.05.051. Epub 2013 May 29.

Carson KR, Bartlett NL, McDonald JR, Luo S, Zeringue A, Liu J, Fu Q, Chang S-H, Colditz GA. Increased body mass index is associated with improved survival in united states veterans with diffuse large B-cell lymphoma. Journal of Clinical Oncology. 2012 Sep; 30(26):3217-22.

Chang S-H, Beason TS, Hunleth JM, Colditz GA. A systematic review of body fat distribution and mortality in older people. Maturitas. 2012 Jul;72(3):175-91.

Chang S-H, Stoll CR, Colditz GA. Cost-effectiveness of bariatric surgery: should it be universally available? Maturitas. 2011 Jul;69(3):230-8.

Dr. Chang on PubMed

Grants and Projects
Agency for Healthcare Research and Quality
K01 HS022330 (Chang: PI) 09/30/13 – 9/29/17
Obesity, comorbidities, and economic evaluations of surgical treatments of obesity
The objective of this project is to systematically investigate the interplay of obesity, comorbidities, and all-cause mortality focusing on how surgical treatments can alter this relationship. The project evaluates different types of bariatric surgery from a population perspective with the goals of identifying the optimal surgical procedure for each obese population and assessing the current NIH guidelines on the eligibility of bariatric surgery.
Role: Principal Investigator

National Institutes of Health
UL1 TR000448 (Chang: PI) 4/10/14 – 4/9/15
Washington University Institute of Clinical and Translational Sciences Just-In-Time Core Usage Program
Surgical complications of hysterectomy by indication for surgery (Goodman: PI)
The aims of this study are to examine (i) the prevalence of total abdominal or radical abdominal hysterectomy by primary indication for hysterectomy and (ii) the length of stay, total costs, and surgical complications in women who underwent a hysterectomy. 
Role: Principal Investigator

National Institutes of Health
U54 CA 155496 (Colditz: PI) 05/01/13 – 6/30/14
Washington University in St. Louis Transdisciplinary Research on Energetics and Cancer Center
Influence of Obesity and Metformin Use on the Transformation of Monoclonal Gammopathy of Undetermined Significance into Multiple Myeloma
The objective of this project is to examine the relationships between obesity, metformin use, and progression from monoclonal gammopathy of undetermined significance to multiple myeloma in a large cohort of the U.S. veterans. Econometric methods that account for potential bias arising from observational data will be used to explore the relationships.
Role: Principal Investigator

National Institutes of Health
UL1 TR000448 01/01/13 – 12/30/13
Washington University Institute of Clinical and Translational Sciences Just-In-Time Core Usage Program
An examination of breast cancer screening through treatment (Goodman: PI)
The goal of this project is to use medical claims data to examine breast cancer screening, treatment, and cancer outcomes. 
Role: Co-investigator

National Institutes of Health
KM1 CA156708 (Fraser: PI) 06/01/12 – 08/31/13
Washington University CER Mentored Career Development Award Program
Comparative Effectiveness of Bariatric Surgery: A Meta-Analysis
The goal of the proposed research is to closely examine the comparative effectiveness of different types of bariatric surgery by evaluating: (1) the risks – peri- and post-operative mortality, complications, and reoperations; and (2) the lifetime benefits – weight loss and remission of obesity-related diseases. 
Role: Scholar