physician photo

Jennifer Ivanovich, MS, MBA, CGC

Assistant Professor of Surgery

Young Women's Breast Cancer Program

Learn more about Jennifer Ivanovich's research

Graduate School

MBA, Business Administration, University of Missouri – St. Louis, 2001

MS, Biology (emphasis in Genetic Counseling), University of Cincinnati, 1992

Board Certifications

1993, American Board of Genetic Counseling, Full Certification

Honors and Awards

2008, Community Service Award: Angel Award, Celebrate Fitness, St. Louis, MO

2006, YWBCP, MAHRPM Show Me Excellence Award, St. Louis, MO

2003, The Woman is Stronger than the Disease, MAHPRM Show Me Excellence Award, St. Louis, MO

Research Interests

Ms. Ivanovich is a board certified clinical cancer genetic counselor and a Research Assistant Professor in the Division of Public Health Sciences, Department of Surgery at Washington University in St. Louis. Ms. Ivanovich provides genetic counseling, assessment and education to individuals with a personal or family history of cancer type. Individuals are evaluated in the Cancer Genetics Clinic at the Siteman Cancer Center, directed by Dr. Alison Whelan, a board certified clinical geneticist. Jennifer’s special clinical interest is in the care of young adults with cancer. Jennifer has been a co-investigator on several cancer genetics studies including studies focused on breast cancer, AML, bone marrow failure, and rare cancer syndromes. Jennifer was a member of the research team responsible for the discovery of the DICER1 gene as the basis for the pleuropulmonary blastoma cancer syndrome. Currently, Jennifer serves as a co-investigator for two studies focused on the identification of novel genetic risk factors for breast cancer development among young breast cancer survivors and a health communications study designed to understand communication preferences regarding information obtained from whole genome sequencing. Ms. Ivanovich is the co-founder and Director of the Young Women's Breast Cancer Program, a community support and education program for women diagnosed prior to 45 years of age. In 2011, Jennifer received a grant from the CDC to expand education services to young adults with cancer. 

Contact Information

660 S. Euclid Avenue
Campus Box 8100
St. Louis, MO 63110
(314) 454-5076

Selected Publications

Ivanovich J, Mallory S, Storer T, Ciske D, Hing A. Clinical Report: 12-year-old male with Elejalde syndrome (Neuroectodermal melanolysosomal disease). Am J Med Genet; 98 313-316, 2000.

Ivanovich J
, Watson M, Whelan A. Brief Clinical Report: An 11-year-old male with mosaic ring chromosome 6 and dilated aortic root. Am J Med Genet;98:182-184, 2000.

Todora H, Skinner C, Gidday L, Ivanovich J, Rawl S, Whelan A. Perceptions of genetic risk assessment and education among first-degree relatives of colorectal cancer patients and implications for physicians. Fam Pract;18:367-372, 2001.

Whelan A, Babb S, Mutch D, Rader J, Herzog T, Todd C, Ivanovich J, Goodfellow PJ. MSI in endometrial carcinoma: MLH1 promoter methylation state is associated with increased familial risk for cancers. Int J Cancer.;99:697-704, 2001.

Ivanovich J, Babb S, Goodfellow PJ, Mutch D, Herzog T, Rader J, Whelan A. Evaluation of the family history collection process and the accuracy of cancer reporting among a cohort of women with endometrial cancer. Clin Can Res;8:1849-1856, 2002.

Wilson D, Ivanovich JL, Whelan A, Goodfellow PJ, Bessler M. Correspondence: Human telomerase RNA mutations and bone marrow failure. Lancet;361:1993-1994, 2003.

Zhou XP, Wiate KA, Pilarski R, Hampel H, Fernandez MJ, Bos C, Dasouki M, Feldman G,Greenberg LA, Ivanovich J, Matloff E, Patterson A, Pierpont ME, Russo D, Nassif N, EngC. Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway. Am J Hum Genet;73:404-411, 2003.

Wicklow BA, Ivanovich JL, Plews MM, Salo TJ, Noetzel MJ, Lueder GT, Cartegn L, Kaback MM, Sandhoff K, Steiner RD, Triggs-Raine BL. Severe subacute GM2 gangliosidosis caused by an apparently silent HEXA mutation (V324V) that results in aberrant splicing and reduced HEXA mRNA. Am J Med Genet;127A:158-66, 2004.

Pham CTN, Ivanovich JL, Raptis SZ, Zehnbauer B, Ley TJ. Papillon LeFevre Syndrome: correlating the Molecular, Cellular, and Clinical Consequences of Cathepsin C/Dipeptidyl Peptidase I deficiency in humans. J Immun;173:7277-7281, 2004.

Du HY, Idol R, Robledo S, Ivanovich J, An P, Londono-Vallejo A, Wilson DB, Mason PJ, Bessler M. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome. Aging Cell;6(5)689-672, 2007.

Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH  McGrath S,  Hickenbotham M, Cook L, Abbott A, Larson DE, Koboldt DC, Pohl C, Smith S Hawkins A, Abbott S, Locke D, Hillier DW, Miner T, Fulton L, Magrini L, Wylie T, Glasscock J, Conyers J, Sander N, Shi X, Osborne JR, Minx P, Gordon D, Chinwalla A, Zhao Y, Ries RE, Payton JE, Westervelt P, Tomasson MH, Watson M, Baty J, Ivanovich J, Heath S, Shannon WD, Nagarajan R, Walter MJ, Link DC, Graubert TA, DiPersio JF, Wilson RK. Whole genome sequencing of an acute myeloid leukemia genome with normalcytogenetics. Nature. 456:66-72, 2008.

Du HY, Pumbo E, Ivanovich J, An P, Maziarz R, Reiss U, Chirnomas D, Shimamura A, Vlachos A, Lipton J, Goyal RK, Goldman F, Wilson DB, Mason PJ, and Bessler M . TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements. Blood. 113(2)309-316., 2009

D. Ashley Hill, M.D., Jennifer Ivanovich, M.S., John R. Priest, M.D., Christina A. Gurnett, MD., Ph.D., Louis P. Dehner, M.D., David Desruisseau, B.S., Jason A. Jarzembowski, M.D.,Ph.D., Brian K. Suarez, Ph.D., Alison J. Whelan, M.D., Gretchen Williams, B.S., Dawn Bracamontes, Yoav Messenger, M.D., Paul J. Goodfellow, Ph.D. Germline DICER1 Mutations in Familial Pleuropulmonary Blastoma. Science 325(5943):965, 2009.

Ding L., Ellis M.J., Li S., Larson D.E. Chen K., Wallis J.W., Harris C.C., McLellan M.D., Fulton R.S., Fulton L.L., Abbott R.M., Hoog J., Dooling D.J., Koboldt D.C., Schmidt H., Kalicki J., Zhang Q., Chen L., Lin L., Wendl M.C., Magrini V.J., Cook L., McGrath S.D., Vickery T.L., Appelbaum E., DeSchryver K., Davies S., Guintoli T., Lin L., Crowder R., Tao Y., Snider J.E., Smith S.M., Dukes A.F., Sanderson G.E., Pohl C.S., Delehaunty K.D., Fronick C.C., Pape K.A. Reed J.S., Robinson J.S., Hodges J.S., Schierding W., Dees N., Shen D., Locke D.P., Wiechert M.E., Eldred J.M., McMichael J., Peck J.B., Oberkfell B.J., Lolofie J.T., Du F., Hawkins A.E., O'Laughlin M.D., Bernard K.E., Cunningham M., Elliott G., Mason M.D., Thompson, Jr. D.M., Ivanovich J.L., Goodfellow P.J., Perou C.M., Weinstock G.M., Aft R., Watson M., Ley T.J., Wilson R.K., Mardis E.R. Genome remodeling in a basal-like breast cancer metastasis and xenograft.  Nature, April 15, 999-1005, 2010.

Link D,  Schuettpelz G,  Shen D, Wang J, Walter J, Kulkarni S,  Payton J, Ivanovich J, Goodfellow P, Le Beau M, Koboldt D, Dooling D,  Fulton R, Bender R, Fulton L, Delehaunty K, Fronick C,  Appelbaum E,  Schmidt H, Abbott R, O’Laughlin M,  Chen K,  McLellan M, Varghese N, Rakesh Nagarajan, Sharon Heath, Timothy A. Graubert, Ding L, Ley T, Zambetti G, Wilson R, Mardis E. The identification of a novel TP53 germline mutation through whole genome sequencing of a patient with therapy-related AML. JAMA, 305(15)1568-1576, 2011.

Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA, Skarlos D, Pectasides D, Fountzilas G, Beckmann MW, Hein A, Ruebner M, Ekici AB, Hartmann A, Schulz-Wendtland R, Renner SP, Janni W, Rack B, Scholz C, Neugebauer J, Andergassen U, Lux MP, Haeberle L, Clarke C, Pathmanathan N, Rudolph A, Flesch-Janys D, Nickels S, Olson JE, Ingle JN, Olswold C, Slettedahl S, Eckel-Passow JE, Anderson SK, Visscher DW, Cafourek VL, Sicotte H, Prodduturi N, Weiderpass E, Bernstein L, Ziogas A, Ivanovich J, Giles GG, Baglietto L,Southey M, Kosma VM, Fischer HP; GENICA Network, Reed MW, Cross SS,
Deming-Halverson S, Shrubsole M, Cai Q, Shu XO, Daly M, Weaver J, Ross E, Klemp J, Sharma P, Torres D, Rüdiger T, Wölfing H, Ulmer HU, Försti A, Khoury T, Kumar S, Pilarski R, Shapiro CL, Greco D, Heikkilä P, Aittomäki K, Blomqvist C, Irwanto A, Liu J, Pankratz VS, Wang X, Severi G, Mannermaa A, Easton D, Hall P, Brauch H, Cox A, Zheng W, Godwin AK, Hamann U, Ambrosone C, Toland AE, Nevanlinna H, Vachon CM, Couch FJ. Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer. Carcinogenesis. 2014 May;35(5):1012-9. doi: 10.1093/carcin/bgt404. Epub 2013 Dec 9. PubMed PMID: 24325915; PubMed Central PMCID: PMC4004200.

Khwaja SS, Ivanovich J, DeWees TA, Ochoa L, Mullen DF, Thomas M, Margenthaler JA, Cyr A, Naughton M, Sanati S, Eberlein TJ, Gillanders WE, Aft RL, Zoberi JE, Zoberi I. Lymphovascular space invasion and lack of downstaging after neoadjuvant chemotherapy are strong predictors of adverse outcome in young women with locally
advanced breast cancer. Cancer Med. 2015 Dec 21. doi: 10.1002/cam4.586. [Epub ahead of print] PubMed PMID: 26687192.

Jennifer Ivanovich on PubMed.

Editorial Positions

2001, American Society of Internal Medicine
Reviewer: Physicians’ Information and Education Resource, Genetic Counseling Module for the American College of Physicians

1998, American Society of Human Genetics
Reviewer: Scientific abstracts submitted to the genetic counseling and genetics education section for the Annual Education Conference.


Whelan AJ, Ivanovich J. Practical Genetics for the Primary Care Physician. In, Adult Psychiatry, Eugene Rubin and Charles Orumski, editors. Chapter 24, 347-363, 2005.

Ivanovich, J. Chapter 14 Genetic Counseling Test Questions. In, DeVita, Hellman and Rosenberg’s Cancer Principles and Practice of Oncology Review, edited by Govindan. 2008.


Ivanovich, J. Breast Cancer Genetics. In, A Woman’s Decision, 4th Edition, 2011. Berger K, Bostwick III J, and Jones G, editors.

Ivanovich, J. Chapter 14 Genetic Counseling Test Questions. In, DeVita, Hellman and Rosenberg’s Cancer Principles and Practice of Oncology Review, edited by Govindan. 2011.

Ivanovich, J. Chapter 14 Genetic Counseling Test Questions. In, DeVita, Hellman and Rosenberg’s CANCER Principles and Practice of Oncology Review, edited by Govindan. Revised 2012.