physician photo

Yan Yan, MD, PhD

Professor of Surgery

Learn more about Dr. Yan's research

Medical School

Medical Degree, Peking Union Medical University, Beijing, China, 1986
M.A., Georgetown University, Washington, D.C., 1993
M.S., Johns Hopkins University, Baltimore, 1995
Ph.D., Johns Hopkins University, Baltimore, 1998

Research Interests

As an epidemiologist and applied biostatistician, Dr. Yan's routine work is to collaborate with clinicians and researchers for study design, data analysis, paper preparations and grant applications in the medical school community, especially in the Cancer Prevention and Control Program at Siteman Cancer Center.

His research interests include competing risks, longitudinal data analyses, developing and validating prognostic models with applications in cancer prevention and treatment as well as applying casual inference theory and methods in comparative effectiveness studies. In addition, Dr. Yan is actively involved in early phase clinical trials at the Siteman Cancer Center.

Epidemiologist/Biostatistician for:

  • R01-Geographic Variation of Breast Cancer Survival
  • R01-Worksite phone counseling for smoking cessation
  • R01-Quality of life over time: DCIS vs early breast cancer
  • R01-Cell cycle variation and metastatic prostate cancer
  • P60-Diabetes research and training center
  • R01-Asthma and Nocturnal Hypoxemia in Sickle Cell Anemia
    development and valiation of predicitve model
  • Risk factor for complications after spine surgery
    • Contact Information

      660 S. Euclid Ave.
      Campus Box 8100
      St. Louis, MO 63110
      (314) 747-1115

      Selected Publications

      Yan Y, Reske KA, Fraser VJ, Colditz GA, Dubberke ER. Using appropriate functional forms for continuous variables and improving predictive accuracy in developing the risk model of Clostridium difficile Infection. Journal of Data Science 2012;10:37-49.

      Pruitt SL, Jeffe DB, Yan Y, Schootman M. Reliability of perceived neighborhood conditions and the effects of measurement error on self-rated health across urban and rural neighborhoods. Journal of Epidemiology and Community Health 2012;66:342-51.

      Wolin KY, Yan Y, Colditz GA. Physical activity and risk of colon adenoma: a meta-analysis. British Journal of Cancer 2011;104:882-885.

      Dubberke ER, Yan Y, Reske KA, Butler AM, Doherty J, Pham V et al. Development and Validation of a Clostridium difficile Infection Risk Prediction Model. Infect Control Hos Epidemio 2011;32(4):360-366

      Hoehner CM, Handy SL, Yan Y, Blair SN, Berrigan D. Association between neighborhood walkability, cardiorespiratory fitness and body-mass index. Social Science and Medicine 2011;73:1707-1716

      Wolin KY, Yan Y, Colditz GA, Lee IM. Physical activity and colon cancer prevention: a meta-analysis. Br J cancer, 2009 Feb;24:100(4):611-6.

      Olsen MA, Krauss M, Agniel D, Schootman M, Gentry CN, Yan Y, Damiano RJ, Jr., Fraser VJ. Mortality associated with bloodstream infection after coronary artery bypass surgery. Clin Infect Dis. 2008;46(10):1537-1546.

      Gao F, Xiong C, Yan Y, Yu K, Zhang Z. Estimating optimum linear combination of multiple correlated diagnostic tests at a fixed specificity with receiver operating characteristics. Jounal of Data Science. 2008;6:1-11.

      Andriole DA, Yan Y, Jeffe DB. Does U.S. Medical Licensing Examination Step l score really matter in surgical residency match outcomes (and should it)? J Am Coll Surg. 2008;206(3):533-539.

      Xiong C, van Belle G, Miller JP, Yan Y, Gao F, Yu K, Morris JC. A parametric comparison of diagnostic accuracy with three ordinal diagnostic groups. Biom J. 2007;49(5):682-693.

      Venkatesh R, Sundaram CP, Figenshau RS, Yan Y, Andriole GL, Clayman RV, Landman J. Prospective randomized comparison of cutting and dilating disposable trocars for access during laparoscopic renal surgery. JSLS. 2007;11(2):198-203.

      Stewart D, Yan Y, Kodner IJ, Birnbaum E, Fleshman J, Myerson R, Dietz D. Salvage surgery after failed chemoradiation for anal canal cancer: should the paradigm be changed for high-risk tumors? J Gastrointest Surg. 2007;11(12):1744-1751.

      Shindel AW, Yan Y, Naughton CK. Does the number and size of veins ligated at left-sided microsurgical subinguinal varicocelectomy affect semen analysis outcomes? Urology. 2007;69(6):1176-1180.

      Schootman M, Sterling DA, Struthers J, Yan Y, Laboube T, Emo B, Higgs G. Positional accuracy and geographic bias of four methods of geocoding in epidemiologic research. Ann Epidemiol. 2007;17(6):464-470.

      Schootman M, Jeffe DB, Gillanders WE, Yan Y, Aft R. The effects of radiotherapy for the treatment of contralateral breast cancer. Breast Cancer Res Treat. 2007;103(1):77-83.

      Pub Med page for Yan Yan, MD, PhD


      Zeller R, Yan Y. Power: Establishing the optimum sample size In: Rao CR, ed. Handbook of Statistics 27-Epidemiology and Medical Statistics. Amsterdam: North-Holland; 2008.