physician photo

Jingqin (Rosy) Luo, PhD

Assistant Professor of Surgery

Graduate School

1998 B.S. Dept. of Statistics, Renmin University, Beijing, China
2001 M.S. Dept. of Statistics, Renmin University, Beijing, China
2003 M.S. Dept. of Statistical Science, Duke University, Durham, North Carolina
2006 Ph.D. Dept. of Statistical Science, Duke University, Durham, North Carolina


Teaching Appointments

2007–2011 Course master, Statistical Computing with SAS, Division of Biostatistics, WUSM
2008–2013 Instructor, Intro to R (R Bootcamp), Division of Biostatistics, WUSM
2012 – Course master, Introduction to Bioinformatics, Division of Biostatistics, WUSM
2012–2014 Instructor, Advanced topics in statistics (Bayesian Statistics module), Division of Biostatistics, WUSM


Research Interests

Dr. Luo's research interests focus on diagnostic tests, change point models and linear mixed effects model, variable/feature selections and predictive models. She has developed statistical measures to summarize diagnostic abilities of markers in three ordinal groups and devised an R package DiagTest3Grp for conducting statistical inference, hypothesis tests and sample size calculation on evaluating diagnostic ability of markers. She has elucidated marker to marker correlations at various hierarchies in clustered studies. Dr. Luo also has expertise in various types of genetic data analysis, causal treatment effect inference in observational studies including propensity score and marginal structural models, conventional survival data analysis. Dr. Luo's current projects include: genetic markers for breast cancer treatment resistance and late relapse; markers that can be targeted to overcome immuno-suppression and improve immunotherapy; genetic markers for gender specific risk of glioblastoma with neurofibromatosis type 1.

Contact Information

(314) 362-3718
jingqinluo@wustl.edu

Selected Publications

Selected Publications (*: co-1st authors)

Ellis MJ, Tao Y, Luo J, A’Hern R, Evans DB, Bhatnager AS, Chaudri Ross HA, von Kameke A, Miller WR, Smith I, Eiermann W, Dowsett M.  Outcome Prediction for ER+ Breast Cancer Based on Post Neoadjuvant Endocrine Therapy Tumor Characteristics. Journal of National Cancer Institute. 2008, 100 (19):1380–1388. PMCID:PMC2556704

Bautista JL, Lio C-WJ, Lathrop SK, Forbush K, Liang Y, Luo J, Rudensky A, Hsieh C-S. Intraclonal competition limits regulatory T cell fate determination in the thymus. Nature Immunology, 2009, 10 (6):610-617. PMCID:PMC2756247

Luo J, Ellis MJ.  Microarray Data Analysis in Neoadjuvant Biomarker Studies in ER+ Breast Cancer. Breast Cancer Research. 2010. 12:112. PMCID: PMC294964

Ellis MJ, Ding L, Shen D, Luo J, Suman V…, Ley TJ, Wilson RK and Mardis ER.  Whole-Genome Analysis Informs Breast Cancer Response to Aromatase Inhibition. Nature. 2012. 486 (7403):353-360. PMID: 22722193.  PMCID: PMC3383766

Luo J and Xiong C.  DiagTest3Grp: An R Package for Analyzing Diagnostic Tests with Three Ordinal Groups. Journal of Statistical Software. 2012. 51(3). PMCID: PMC3595562

Xiong C, Luo J, Gao F, Chen L and Yan Y.  Optimum Design of Disease-Modifying Trials on Alzheimer's Disease. Statistics in Biopharmaceutical Research, 2012 4(3):216-227.  PMCID:PMC3634601

D’Angelo G, Luo J, Xiong C.  Missing Data Methods for Partial Correlations. Journal of Biometrics & Biostatistics, 2012, 3(8). PMCID: PMC3772686

Chimge N-O, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman B, Tripathy D, Ellis MJ and Frenkel B.  Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness.  Clinical Cancer Research 2012. 18(3). PMCID:PMC3277803

Luo J and Xiong C. Youden Index and Associated Cutoff Points for Three Ordinal Diagnostic Groups. Communications In Statistics---Simulation and Computation. 2013. 42 (6) p1213-1234. PMCID: PMC3685301.

Xiong C,  Luo J, Gao F, Morris J. Optimizing parameters in clinical trials with a randomized start or withdrawal design. Computational statistics and Data Analysis, 2013, 69, 101-113 

Warrington, N. M.(*), Sun, T (*), Luo, J (*), Mason, C. C., Parkin, P.C., McKinstry, R.C, Ganzhorn, S., Spoljaric, D, Albers, A, Merkelson, A., Forys, J.T, Tabori, U, Allen, J. C., Schiffman, J.D, Gutmann, D. H. and Rubin, J. B. The Cyclic AMP pathway is a sex-specific modifier of glioma risk in Neurofibromatosis type 1. Cancer Research.  2014.75(1):16-21. PMCID: PMC4286430

Schenone, AD (*), Luo, J (*), Montgomery, LM., Morgensztern, D., Adkins, D., Van Tine, BA. Risk-Stratified Patients with Resectable Soft Tissue Sarcoma Benefit from Epirubicin-Based Adjuvant Chemotherapy, Cancer Medicine, 2014. 3(3): 603-612. PMCID: PMC4101751

Lee S, Stewart S, Nagtegaal I, Luo J, Wu Y, Colditz G, Medina D, Allred DC.  Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma in Situ to Invasive Breast Cancer. Cancer Research, 2012. PMCID: PMC3899801

Chan SR, Vermi W, Luo J, Lucini L, Rickert C, Fowler AM, Lonardi S, Arthur C, Young LJT, Sharp TL, Levy DE, Welch MJ, Cardiff RD and Schreiber RD.  STAT1-Deficient Mice Spontaneously Develop Estrogen Receptor -Positive Luminal Mammary Carcinomas. Breast Cancer Research 2012, 14:R16. PMCID: PMC3496133

Luo, J, D'Angela G,Gao F, Ding J, Xiong C.  Bivariate Correlation Coefficients in Family-type Clustered Studies. 2015. The Biometrical Journal (in press)

Editorial Positions

Statistician on Editorial Board: Journal of  Orthopaedic Trauma:  2006 - present

Regular Reviewer
  • Computational Statistics & Data Analysis (Elsevier): 2008 - present
  • Bioinformatics: 2009 - present
  • Journal of Clinical Oncology : 2013 - present
  • Breast Cancer Research: 2014 - present
  • PLoS one: 2014 - present 
  • PLoS Computational Biology: 2014 - present
  • JAMA Oncology: 2015 - present
  • American Journal of Hypertension: 2015 - present
  • BMC Bioinformatics: 2015 - present